日本質量分析学会 第66回質量分析総合討論会

Program

Oral Sessions  Day 4, May 18(Fri.)

  • The mark "☆" shows that the presenting author applied to the "Best Presentation Award".
[4A-O1-P] PTM proteomics & functional proteomics
Room A (OrBit Hall) 09:00-11:00
Chair: Jun Adachi (NIBIOHN) / Kazuishi Kubota (Daiichi Sankyo RD Novare)

4A-O1-P-0900      09:00-09:20  

Global Identification and Functional Characterization of Protein Kinase Substrates using Various Phosphoproteomic Technologies

(Tokushima Univ.)
oHidetaka Kosako

4A-O1-P-0920      09:20-09:40  

Phosphorylation Network Analysis Based on Kinome Profiling

(Kyoto Univ.)
oNaoyuki Sugiyama, Haruna Imamura, Dai Sakamoto, Junna Nakazono, Kazutaka Yachigo, Chisato Takahashi, Hsin-yi Chang, Yasushi Ishihama

4A-O1-P-0940      09:40-10:00  

Phosphoproteomics of non-small-cell lung cancer cells treated with erlotinib reveals drug-resistant signatures and potential targets

(NIBIOHN)
oJun Adachi, Yuichi Abe, Maiko Nagano, Ayako Sato, Marina Kishida, Takeshi Tomonaga

4A-O1-P-1000(2P-55)      10:00-10:20  

☆An improved method for cell type-specific glycomic analysis of formalin-fixed paraffin-embedded tissue sections in combination with histochemical stainingAn improved method for cell type-specific glycomic analysis of formalin-fixed paraffin-embedded

(AIST)
oChiaki Nagai-okatani, Misugi Nagai, Atsushi Kuno

4A-O1-P-1020      10:20-10:40  

Selective Degradation of Splicing Factor CAPERα by Anticancer Sulfonamides

(1Eisai, 2Hyogo University of Health Science)
oTaisuke Uehara1, Yukinori Minoshima1, Koji Sagane1, Naoko Hata1, Kaoru Mitsuhashi1, Noboru Yamamoto1, Hiroshi Kamiyama1, Kentaro Takahashi1, Yoshihiko Kotake1, Mai Uesugi1, Akira Yokoi1, Atsushi Inoue1, Taku Yoshida1, Miyuki Mabuchi2, Akito Tanaka2, Takashi Owa1

4A-O1-P-1040      10:40-11:00  

Applications of proteomics for drug discovery and development

(DS RD Novare)
oKazuishi Kubota

[4A-L-P] AOHUPO session 2 (Supported by Thermo Fisher Scientific K.K.)
Room A (OrBit Hall) 12:10-13:10
Chair: Yu-Ju Chen (Academia Sinica)

4A-L-P-1210   12:10-12:20  

Introduction

4A-L-P-1220      12:20-12:40  

High Efficient and Precise Glycoproteomic Analysis with Intelligent Technology

(1Fudan IBS, 2CAS Computing Tech)
oPengyuan Yang1, Weiqian Cao1, Mingqi Liu1, Wenfeng Zeng2, Chao Liu2, Pan Fang1, Huali Shen1, Simin He2

4A-L-P-1240      12:40-13:00  

Development of salivary protein biomarkers for oral cancer

(1Chang Gung University, 2Chi-Mei Medical Center, 3Chang Gung Memorial Hospital)
oJau-song Yu1, Yung-chin Hsiao1, Lichieh Julie Chu1, Yi-ting Chen1, Wei-fang Chiang2, Kai-ping Chang3, Chang Gung Oscc Biosignatures Team1

4A-L-P-1300      13:00-13:10  

Development of ELISA assay by eiptope mapping of CagA protein recognized by antibodies in sear for the prevention of Japanese children from chronic infection of Helicobacter pylori

(1Tokuyama Ishikai Hosp., 2DENKA SEIKEN Co. Ltd., 3Tokuyama ishikai Hosp., 4Tanimura Clinic for Paediatrics)
oKazuyuki Nakamura1, Takamichi Takahashi2, Toshiko Fujii3, Satoshi Tanimura4

[4A-O2-P] What everyone ought to know about the recent progress and perspectives of disease proteomics
Room A (OrBit Hall) 14:25-16:25
Chair: Tadashi Kondo (National Cancer Center)

4A-O2-P-1425      14:25-15:05   [Keynote]

A Proteomic Landscape of Diffuse-type Gastric Cancer

(1BPRC, 2BCM)
oJun Qin1,2, Bei Zhen1

4A-O2-P-1505      15:05-15:25  

Systematic discovery of cancer biomarkers by integrative post-translational modification-directed proteomics

(Univ. Tokyo)
oMasaaki Oyama, Hiroko Kozuka-hata

4A-O2-P-1525      15:25-15:45  

Development of enzymomics approach to search for disease-related alternation of enzymatic functions

(1Univ. Tokyo, 2Univ. Tokyo, 3Univ. Tokyo, 4sainome, 5AMED-CREST)
oToru Komatsu1, Jun Onagi1, Yuki Ichihashi1, Koichi Yanagi1, Shusuke Ogihara1, Makiko Kawamura4, Masahiro Shimoda4, Tetsuo Nagano3, Yasuteru Urano2,5

4A-O2-P-1545      15:45-16:05  

A functional role of LEFTY as a molecular marker for ovarian clear cell carcinoma

(1Kitasato Univ., 2RIKEN IMS, 3Kitasato Univ.)
oToshihide Matsumoto1, Masashi Akiya1, Yusuke Kawashima2, Yoshio Kodera3, Ako Yokoi1, Yasuko Oguri1, Miki Hashimura1, Makoto Saegusa1

4A-O2-P-1605      16:05-16:25  

Proteogenomics for sarcoma research: International Cancer Proteogenomics Consortium (ICPC)

(1NCCRC, 2IUHW)
oTadashi Kondo1, Enu Hattiru1, Kumiko Shiozawa1, Masayha Ono1, Mari Masuda1, Teshi Yamada2

[4B-O1-P] JPrOS Young researchers in proteomics
Room B (Seiun 1) 09:00-11:00
Chair: Yuichi Abe (NIBIOHN)

4B-O1-P-0900(2P-56)      09:00-09:15  

☆Comprehensive phosphoproteomics from biopsy specimens

(1NIBIOHN, 2Natl. Cancer Ctr. Hosp.)
oYuichi Abe1, Hirokazu Syoji2, Hirano Hirano2, Jun Adachi1, Narikazu Boku2, Takeshi Tomonaga1

4B-O1-P-0915(2P-57)      09:15-09:30  

☆Establishment of method for peptidome analysis from a small amount of tissue

(1Kitasato Univ., 2Clin. Prot. Ctr., 3Kitasato Univ.)
oYuzuru Nakagawa1, Takuya Yamada1, Takaki Tsunoda1, Kazumi Fujimoto1,2, Makoto Itakura3, Yoshio Kodera1,2

4B-O1-P-0930(2P-58)      09:30-09:45  

☆Quantitative proteomic assessment of differences and stability of human serum and plasma proteins

(Kumamoto Univ.)
oMadoka Nambu

4B-O1-P-0945(2P-59)      09:45-10:00  

☆Development and application of strategy for comparative analysis of protein expression and functional state.

(1Kitasato Univ., 2Kitasato Univ., 3Clin. Prot. Ctr.)
oRyo Konno1, Kana Hiramatsu1, Hiroaki Itou1, Masataka Higuchi1, Makoto Itakura2, Yoshio Kodera1,3

4B-O1-P-1000(2P-60)      10:00-10:15  

☆Identification of internalized plasma membrane proteins in human brain capillary endothelial cells.

(Kumamoto Univ.)
oMariko Oishi

4B-O1-P-1015      10:15-10:30  

Drought stress characterization of tolerant and sensitive barley genotypes through Proteomics analysis

(1UAJK, 2PMASAAUR, 3NARC, 4UoT)
oRehana Kausar1, Muhammad Arshad2, Armghan Shahzad3, Setsuko Komatsu4

4B-O1-P-1030(2P-61)      10:30-10:45  

☆Comparative Phosphoproteomic Analysis of Fresh and After-ripened Barley seeds

(1TUAT, BASE, 2RIKEN CSRS, 3CSIRO, 4Max Planck Institute, 5Okayama Univ., 6Missouri Univ., 7JST・PRESTO)
oShinnosuke Ishikawa1, Fuminori Takahashi2, Jose Barrero3, Hirofumi Nakagami4, Takashi Hirayama5, Scott Peck6, Frank Gubler3, Kazuo Shinozaki2, Taishi Umezawa1,7

4B-O1-P-1045      10:45-11:00  

Soybean Proteomics: A Leading Tool in Exploring Effects of Flooding Stress using Proteomic Technique

(1KUST, 2Botany, KUST, 3B & GE, KUST, 4University of Tsukuba, Japan)
oAmana Khatoon1, Shafiq Rehman2, Muhammad Jamil3, Setsuko Komatsu4

[4B-O2-P] Cellular network analysis based on proteomics
Room B (Seiun 1) 14:25-16:25
Chair: Naoyuki Sugiyama (Kyoto Univ.) / Shinya Ohta (Kochi Univ.)

4B-O2-P-1425(2P-62)      14:25-14:45  

☆Ribosomics reveals a novel mechanism for translational regulation

(1Kyoto Univ., 2MDC, 3Kyushu Univ.)
oKoshi Imami1,2, Miha Milek2, Boris Bogdanow2, Tomoharu Yasuda2,3, Yasushi Ishihama1, Markus Landthaler2, Matthias Selbach2

4B-O2-P-1445(4P-39)      14:45-15:05  

☆TMT-based Quantitative Mass Spectrometry Reveals Proteomic Shifts between Traditional Hydrated Biofilm and DSB from Staphylococcus aureus: One Step Forward with Dry Surface Biofilm (DSB)

(1Macquarie Uni, 2APAF)
oMd Arifur Rahman1, Durdana Chowdhury1, Ardeshir Amirkhani2, Honghua Hu1, Mark Molloy2, Dana Pascovici2, Mark Baker1, Maria Mempin1, Xiaomin Song2, Karen Vickery1

4B-O2-P-1505      15:05-15:25  

Surface Proteome Profiles Meet Adipocyte Commitment

(Kyoto Univ.)
oHsin-yi Chang, Naoyuki Sugiyama, Yasushi Ishihama

4B-O2-P-1525      15:25-15:45  

Identification of pathogenic mutations in patients with rare diseases using multiomics approaches

(Nagoya Univ.)
oYasuyoshi Oka, Tomoo Ogi

4B-O2-P-1545      15:45-16:05  

High-throughput biosynthesis of stable isotope-labeled internal standards for global proteome quantification

(Ehime Univ.)
oNobuaki Takemori

4B-O2-P-1605      16:05-16:25  

Mass spectrometry-based proteogenomic analysis to identify novel protein-coding genes through the human proteome

(Kyung Hee University)
Seung-eun Lee, oMin-sik Kim

[4C-O1-P] Role of mass spectrometry in the development and control of antibody drugs
Room C (Seiun 2) 09:00-11:00
Chair: Haruhiko Kamada (NIBIOHN) / Susumu Uchiyama (Osaka Univ.)

4C-O1-P-0900      09:00-09:20   [Invited]

In vitro Affinity Maturation of Catalytic Antibodies against Transition-state Analogues

(Osaka Pref. Univ.)
oIluo Fujii

4C-O1-P-0920      09:20-09:40  

Target discovery method to stromal tissue for development of antibody drugs

(1NIBIOHN, 2Osaka Univ.)
oHaruhiko Kamada1, Tsuyoshi Inoue2

4C-O1-P-0940      09:40-10:00  

Characterization of the active catabolite formed in vivo from an Antibody Drug Conjugate with an Eg5 Inhibitor Payload and Stable Linker Design

(Novartis)
oPatrick Rudewicz, Qin Yue, Ying-bo Chen, Suzanna Clark, Peiyin Wang, William Mallet, Dylan Daniel, Grazia Piizzi, Cristina Nieto-oberhuber

4C-O1-P-1000      10:00-10:20  

Evaluation of Chemical Stability of Therapeutic Antibodies using High-Resolution Mass Spectrometry

(Osaka Univ.)
oKayoko Hayashihara, Koya Shintani, Takahiro Maruno, Susumu Uchiyama

4C-O1-P-1020      10:20-10:40  

Monitoring Multiple Critical Quality Attributes of mAbs at Subunit and Peptide Level Using a Compliant Ready High Resolution LC/MS Platform

(1Nihon Waters, 2Waters)
oKenji Hirose1, Jing Fang2, Nilini Ranbaduge2, Henry Shion2, Min Du2, Ying Yu2, Scott Berger2, Weibin Chen2

4C-O1-P-1040      10:40-11:00  

Characterization of Biopharmaceuticals: Development of Disulfide Linkage Analysis Method for Human Hepatocyte Growth Factor

(Eisai)
oEmiko Yamauchi, Yasushi Shikata

[4C-O2-P] Mass spectrometry and omics research from information science
Room C (Seiun 2) 14:25-16:25
Chair: Shujiro Okuda (Niigata Univ.) / Akiyasu Yoshizawa (Kyoto Univ.)

4C-O2-P-1425      14:25-15:05   [Keynote]

Analysis of Measurement Data via Sparse Modeling

(Kyoto Univ.)
oToshiyuki Tanaka

4C-O2-P-1505      15:05-15:25  

Integrated characterisation of human cancer cell lines using public proteomics data

(EMBL-EBI)
oAndrew Jarnuczak, Juan Vizcaino

4C-O2-P-1525      15:25-15:45  

Exploring the prostate and urinary glycoproteome for novel prostate cancer biomarkers

(1USP, 2MQ, 3FMUSP, 4USD, 5UFRJ)
oRebeca Sakuma1, Fabio Ortega3, Saulo Recuero3, Christopher Ashwood2, Hannes Hinneburg2, Livia Fernandes4, Gilberto Domont5, Fabio Nogueira5, Martin Larsen4, Miguel Srougi3, Katia Leite3, Nicolle Packer2, Morten Thaysen-andersen2, Giuseppe Palmisano1

4C-O2-P-1545      15:45-16:05  

When is a Biomarker not a biomarker? The problems of interpreting statistical data in Discovery ‘Omics analysis.

(Waters)
oPaul Goulding

4C-O2-P-1605(4P-40)      16:05-16:25  

☆Application of Non-negative Matrix Factorization in Mass Spectrometry-Based Shotgun Proteomics

(1Grad. Pharm. Sci., Kyoto Univ., 2Grad. Informatics, Kyoto Univ., 3RIKEN)
oPasrawin Taechawattananant1, Akiyasu Yoshizawa1, Kazuyoshi Yoshii2,3, Yasushi Ishihama1