The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Poster Presentations

Day 3, June 24（Fri.）　　Room P (501, 502 and 503)

3P-33　　PDF

A novel pyridinium derivatization reagent for high-sensitive detection of polycarboxylic acids using liquid chromatography-electrospray ionization-tandem mass spectrometry

(Fukuoka Univ.)
oShimba Kawasue, Yohei Sakaguchi, Reiko Koga, Hideyuki Yoshida, Hitoshi Nohta

Due to the high polarity, short-chain fatty acids are difficult to analyze with LC-ESI-MS, therefore various derivatization methods have been reported. However, there are few analytical methods for polycarboxylic acids with multiple carboxy groups. Therefore, we synthesized a novel derivatization reagent for polycarboxylic acid. This derivatization reagent has high reactivity and ESI efficiency, and multiple introduction of the reagent into analyte gives higher ESI efficiency. Therefore, the derivatization reagent was particularly effective against polycarboxylic acids.