The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Poster Presentations

Day 3, June 24（Fri.）　　Room P (501, 502 and 503)

3P-09　　PDF

Quantification of glycerophospholipid isomers using data-independent acquisition (DIA)

(1Osaka Univ., 2Osaka Univ., 3Osaka Univ., 4Shimadzu)
oDaiki Hara1, Shuka Komori1, Nobuyuki Okahashi1,2,3, Atsuhiko Toyama4, Junko Iida2,4, Fumio Matsuda1,2,3

The data-independent acquisition (DIA) mode of tandem mass spectrometry was applied for the separation of structural isomers of glycerophospholipids in Saccharomyces cerevisiae and human plasma. The parameters of DIA were optimized by a performance comparison with the data-dependent acquisition mode. Separation and relative quantification of co-eluting structural isomers was achieved by the detection of specific fragment ions from the DIA data.