The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan

Abstract

Poster Presentations

Day 2, June 23(Thu.)  Room P (501, 502 and 503)

Analysis of anti-diabetic components in green tea by metabolic profiling

(Kyushu Univ.)
oYoshinori Fujimura, Mototsugu Watanabe, Tomomi Ichinose, Mao Yamamoto, Motofumi Kumazoe, Hirofumi Tachibana

The inhibition of dipeptidyl peptidase (DPP)-IV enzyme plays an essential role in controlling hyperglycemia in diabetes mellitus. Although green tea (Camellia sinensis L.) has been reported to possess the DPP-IV inhibitory activity, there are no reports of the comparison among green tea cultivars or the identification of their active components. We have reported that metabolic profiling (MP) technique, which visualizes the potential relationship between the amount of samples and their bioactivity, is effective in assessing the functionality of foods/agricultural products and identifying the components involved in the functionality. However, there is no report on MP-driven bioactivity evaluation of green tea cultivars related to the DPP-IV inhibitory activity. Here, we evaluated the DPP-IV inhibitory activity of 43 green tea cultivars and found the bioactivity-related components and combinations by using MP technique.