The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Poster Presentations

Day 2, June 23（Thu.）　　Room P (501, 502 and 503)

2P-24　　PDF

Dissecting Global Metabolomics of the Mouse Brain with Tumor Model through Mass Spectrometry Imaging

(1Doshisha Univ., 2Kyoto Univ., 3Shimadzu)
oNao Kobayashi1, Natsuko Kondo2, Kosuke Kurosaki1, Yoshinori Sakurai2, Minoru Suzuki2, Shinichi Yamaguchi3, Masaya Ikegawa1

Here we apply an untargeted mass spectrometry-based metabolomics approach by imaging mass spectrometry in combination with UMAP method. The current protocol enabled to visualize differences in broad array of metabolites across anatomical regions of the mouse brain. This study yields important platform of metabolomics phenotyping of the mouse brain by defining regional homeostasis for the normal mouse brain to give context to the reaction to brain tumor as well as boron neutron capture therapy.