The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Poster Presentations

Day 2, June 23（Thu.）　　Room P (501, 502 and 503)

2P-18　　PDF

Quantitative Analysis of Steroids in Serum Using Liquid Chromatography-Mass Spectrometry with Ion Mobility

(1Toyama Pref. Univ., 2Kanazawa Univ.)
oMai Yamakawa1, Shigehiro Karashima2, Issey Osaka1

The quantitative analysis of steroids is vital for the diagnosis of familial hyperaldosteronism type I, primary aldosteronism, Cushing's disease, etc. Generally, the steroids were analyzed by LC/MS/MS with MRM. It is important to analyze the steroids with quantitation and evaluation unexpected compounds simultaneously for future metabolomics. For the simultaneous analysis, quantitative analysis method is required without MS/MS. In this study, we analyzed steroids in serum using LC/MS with ion mobility. The method allowed to detect with high sensitivity and selectivity.