The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Poster Presentations

Day 1, June 22（Wed.）　　Room P (501, 502 and 503)

1P-37　　PDF

Quantitative Proteomics by Data-independent Acquisition to Elucidate the Regulatory Mechanism of Neural Stem Cell Differentiation of Human Induced Pluripotent Stem Cells

(Yokohama City Univ.)
oTakaya Urasawa, Takumi Koizumi, Kazumasa Kimura, Yuki Ohta, Nana Kawasaki

Human induced pluripotent stem cells (iPSCs)-derived neural differentiated cells are expected to be applied to regenerative medicine and understanding the mechanisms of neural differentiation of iPSCs is important for their implementation. In this study, we conducted LC/MS/MS with a data-independent acquisition (DIA-MS) approach for comparative proteomics of iPSCs and neural stem cells (NSCs). We found trophoblast glycoprotein (TPBG) control differentiation in NSCs with Wnt/β-catenin pathway inhibition.