Oral Sessions (Day1, Day2, Day3)
Poster Presentations (Day1, Day2, Day3)
Poster Presentations
- Day 1, June 22（Wed.） Room P (501, 502 and 503)
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1P-33 PDF
The effect of orthokeratology lens wear on the proteins of tear fluid
Contact lenses are classified into soft contact lenses including hydrogel contact lens (HyCL) and silicone hydrogel contact lens (SiHyCL), and rigid gas-permeable contact lens including orthokeratology (OK) lens; OK is a method that uses specially designed gas-permeable contact lenses overnight to reshape the cornea to temporarily reduce or eliminate myopia. In this study, the effect of OK lens wear was investigated on the protein of tear fluid. Nine subjects between age 25 to 44 were recruited. They were classified into HyCL wearer group (n=3), SiHyCL wearer group (n=3) and control group without lens wear (n=3). All groups worn OK lenses for 2-months, and tear samples were collected at 0 day and after 2-months OK lens wearing. The proteins of tear fluid were compared on following conditions: 1) control group, HyCL wearer group and SiHyCL wearer group, 2) pre-OK wearing (baseline) and post-OK lens wearing (after 2 -months OK lens wearing). As the results, HyCL, SiHyCL and OK lens wearing altered the protein profile of tear fluid. The differentially expressed proteins (up and down) may play a potential role to maintain a healthy eye balance for safe use of contact lens.