The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Poster Presentations

Day 1, June 22（Wed.）　　Room P (501, 502 and 503)

1P-12　　PDF

Effect of Probe Vibration Frequency on Mass Spectrometry Imaging by Tapping-mode Scanning Probe Electrospray Ionization

(1Osaka Univ., 2Osaka Univ., 3Osaka Univ.)
oMengze Sun1, Yoichi Otsuka1, Nijiho Ote2, Shuichi Shimma3, Michisato Toyoda1

Mass spectrometry imaging is an analytical method to measure the multi-components distributed in sample. Tapping-mode scanning probe electrospray ionization (t-SPESI) realizes the direct extraction and ionization using vibrating capillary probe and pico-liter solvent. Different driving frequency have different initial amplitude. Because the force between the probe and sample will shift the Q-curve, Different driving frequency also have different vibration mode, which could affect the probe approaching and the stability of feedback system. Our research is using different probe driving frequency to conduct the mass spectrometry imaging by t-SPESI. To find what kind of influence brought by changing the driving frequency and what is the best condition for mass spectrometry imaging for t-SPESI. Now, the conclusion is that using resonant driving frequency is better than higher or lower frequency.