The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Poster Presentations

Day 1, June 22（Wed.）　　Room P (501, 502 and 503)

1P-11　　PDF

Selectivity of Solvents for Mass Spectrometry Imaging by Tapping-mode Scanning Probe Electrospray Ionization

(1Osaka Univ., 2Osaka Univ., 3JST・PRESTO, 4Osaka Univ.)
Nijiho Ote1, oYoichi Otsuka2,3, Mengze Sun2, Shuichi Shimma4, Michisato Toyoda2

Tapping-mode scanning probe electrospray ionization (t-SPESI) is a extraction-ionization technique using picoliter solvents, which can be applied to mass spectrometry imaging (MSI). Positive ion mode MSI of mouse brain tissue sections was studied using DMF/MeOH binary mixtures and their respective pure solvents. The mixed solvent was found to have the highest number of ion peaks detected, and the physicochemical properties of the solvent were found to influence the extraction and ionization in t-SPESI.