The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Oral Sessions

Day 1, June 22（Wed.）　18:15-18:30　Room D (413 and 414)

1D-O1-1815（1P-49）　　PDF

Flavan 3-ols as a stressor improves brain function via the locus coeruleus-noradrenergic systems

(1Shibaura Inst. Tech., 2Fukushima Univ.)
oYasuyuki Fujii1, Jun Sakata1, Orie Muta1, Kazuki Sakata1, Minayu Odaka1, Shu Taira2, Naomi Osakabe1

We have previously found that the intake of flavan 3-ols, a polyphenol with a strong astringent taste, enhances sympathetic nerve activity and has beneficial effects on circulation and metabolism. In general, a stressor activates the central nervous system resulting in improvement of cognitive function, besides sympathetic nerve activation as a stress response. Therefore, we examined the effects of flavan 3-ols on the central stress response and cognitive function in experimental animals. As a result, we found that flavan 3-ols induced a stress response and stimulated the locus coeruleus, resulting in the projection of noradrenaline to the entire brain and improved cognitive function.