The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan

Abstract

Oral Sessions

Day 1, June 22(Wed.) 17:00-17:15 Room D (413 and 414)

Nano-PALDI analysis for hair components

(1Fukushima. Univ., 2Y.A.C.)
oYuki Kusano1, Hitomi Shikano1, Nobuyuki Takahashi2, Shu Taira1

Using a vertical hair-slice section, we compared the components of normal and damaged hair regions using two ionization methods, matrix-assisted laser desorption/ionization and nanoparticle-assisted laser desorption/ionization (nano-PALDI) mass spectrometry. Nano-PALDI is useful for small-molecule and high spatial resolution (5 μm) analyses due to the lack of noise. Thus, clear images were obtained from thin hair samples. In nano-PALDI mass spectrometry imaging, cystine and 18-methyleicosanoic acid as endogenous hair components localized in the cuticle and cortex and cuticle of normal hair, respectively. In contrast, both components were absent in damaged hair.