The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Oral Sessions

Day 1, June 22（Wed.）　16:45-17:00　Room D (413 and 414)

1D-O1-1645（1P-43）　　PDF

Analysis of the effect of theanine for catecholamines in the brain

(1Fukushima Univ., 2TAIYO KAGAKU)
oMakoto Muto1, Hitomi Shikano1, Aya Abe2, Makoto Ozeki2, Shu Taira1

L-Theanine (theanine) is a derivative of glutamic acid, which is abundant in tea leaves and contributes to the umami and sweetness of tea. In recent years, its effects on the brain, such as relaxation, have been attracting attention. In this study, we used imaging mass spectrometry to visually analyze the changes in the catecholamine system in the brain after the administration of theanine (30, 60, and 90 minutes after administration). In IMS, we applied derivatization reagent to improve detection limit. Simultaneous imaging of L-dihydroxyphenylalanine (L-DOPA), dopamine (DA) and norepinephrine (NE) on the catecholamine metabolic pathway is particularly useful because L-DOPA is an important metabolic intermediate.