Oral Sessions (Day1, Day2, Day3)
Poster Presentations (Day1, Day2, Day3)
Plenary Lectures
- Day 1, June 22（Wed.） 10:15-11:00 Room A (Main Hall)
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1A-PL-1015 PDF
Micro Crystalline Sponge Method (MicroCS Method): X-ray Molecular Structure Analysis with MS-quantity Samples
We have developed a new protocol for SCD analysis that does not require the crystallization of the sample. In the method (called crystalline sponge- or CS-method), tiny crystals of porous complexes (CSs) are soaked in the solution of a target, where the complexes can absorb and orient the target molecules in the pores. The subsequent crystallographic analysis clearly determines the absorbed guest structures along with the host frameworks. As the SCD analysis is carried out with only one tiny crystal, the required sample amount is of the nano-to-microgram order. By using micrometer-sized CSs and multi-data collection at synchrotron facilities (SP-ring 8 and KEK), the CS method can analyze trace amount samples even at below nano-gram scale. Micro Electron Diffraction (ED) analysis makes it possible to analyze trace samples on the femto- to pico-gram scale, comparable to MS sensitivity.