日本質量分析学会 第70回質量分析総合討論会会

演題概要

ポスター発表

第3日 6月24日(金)  P会場(501,502,503)

イオンモビリティーLC/MSを用いた血漿中のアミノ酸とその他の代謝物の同時分析

(1富山県立大2金沢大国基)
o山﨑海斗1唐島成宙2大坂一生1

In quantitative analysis of amino acids using LC/MS/MS, multiple ion monitoring (MRM) method has been used for highly sensitive and selective detection. In this method, it is possible to analyze about 30 kinds of compounds in one analysis. For the MRM analysis, it is needed to determine the target analytes before the measurement. Therefore, unknown and unexpected metabolites could not be analyzed by MRM. Since comprehensive analysis is required to elucidate the disease in metabolomics, not only amino acids but other compounds such as lipids should be detected. In this study, we suggest the LC/MS with ion mobility for highly sensitive and selective non-target analysis.