日本質量分析学会 第70回質量分析総合討論会会

演題概要

オーラルセッション

第3日 6月24日(金) 9:20~9:40 C会場(411,412)

MetaboBank:メタボローム研究のための一次レポジトリおよび統合データベース

(1遺伝研2かずさDNA研3京大生存研4理研5京府大生命環境6奈良先端大)
o時松敏明1児玉悠一1福田亜沙美1藤澤貴智1長崎英樹2荒武2,3高橋みき子4大澤祥子2小林紀郎4櫻井望1福島敦史4,5金谷重彦6平川英樹2有田正規1,4

MetaboBank is a database including primary repository for metabolome research and related secondary databases for metabolome research.
We launched the first version of MetaboBank repository in October 2020 at DNA Data Bank of Japan (DDBJ) Center. One year later, we have upgraded MetaboBank to version 2 to enhance integration with other biological resources by using standard metadata format with links to BioProject and BioSample records. The new metadata format is based on MAGE-TAB which has been used by functional genomics databases such as ArrayExpress of European Bioinformatics Institutes (EBI) and Genomic Expression Archive (GEA) of DDBJ Center. EBI’s metabolomics database MetaboLights has used ISA-TAB which is an abstracted model of MAGE-TAB. Recently, “SDRF-proteomics” has been developed based on MAGE-TAB as proteomics metadata format and used by EBI’s proteomics database PRIDE. The new MetaboBank MAGE-TAB format allows easier integration with these “omics” database using MAGE-TAB-based formats. The new MetaboBank data are linked with BioProject and BioSample records to realize integration with metabolomics data and related nucleotide sequencing data in INSDC. Public MetaboBank data are provided in Resource Description Framework (RDF) format in addition to MAGE-TAB for semantic integration with National Bioscience Database Center (NBDC) resources.