日本質量分析学会 第70回質量分析総合討論会会

演題概要

オーラルセッション

第3日 6月24日(金) 14:40~15:00 A会場(メインホール)

次世代サプレッサーを搭載したイオンクロマトグラフィー高分解能タンデム質量分析 (IC/HRMS/MS) による超網羅的な親水性メタボローム分析法の開発

(1九大生医研2サーモフィッシャー)
o高橋政友1鈴木隆弘2高原健太郎2馬場健史1和泉自泰1

The rapid development of liquid chromatography mass spectrometry techniques has contributed to the accurate detection and identification of hydrophilic metabolites in various biological samples. However, since these hydrophilic metabolites have a wide variety of physicochemical properties, a generally applicable analytical system for the comprehensive and highly sensitive measurement of hydrophilic metabolites has not been developed. The aim of this study is to develop an advanced analytical system for ultra-comprehensive hydrophilic metabolome analysis by two ion chromatography high-resolution tandem mass spectrometry (IC/HRMS/MS) equipped with novel cationic or anionic suppressors.