演題概要

ポスター発表

第2日　6月23日（木）　　P会場（501，502，503）

2P-18　　PDF

イオンモビリティーを用いたLC/MSによる血清中のステロイドホルモンの定量分析の可能性

(¹富山県立大院工・ ²金沢大)
^o山川舞¹・ 唐島成宙²・ 大坂一生¹

The quantitative analysis of steroids is vital for the diagnosis of familial hyperaldosteronism type I, primary aldosteronism, Cushing's disease, etc. Generally, the steroids were analyzed by LC/MS/MS with MRM. It is important to analyze the steroids with quantitation and evaluation unexpected compounds simultaneously for future metabolomics. For the simultaneous analysis, quantitative analysis method is required without MS/MS. In this study, we analyzed steroids in serum using LC/MS with ion mobility. The method allowed to detect with high sensitivity and selectivity.