演題概要

オーラルセッション

第2日　6月23日（木）　9:45～10:00　D会場（413，414）

2D-O1-0945（2P-46）　　PDF

北アフリカ棲息種サソリCompsobuthus werneriの毒液に含まれる新規殺虫性ペプチドの探索と構造決定

(¹京大院農・ ²Al-Azhar Univ.)
^o中道隆哉¹・ Megaly, Alhussin²・ Abdel-Wahab, Mohammed²・ 宮下正弘¹・ 中川好秋¹・ 宮川恒¹

The main components of scorpion venom are peptides, which are known to exhibit various biological activities, such as insecticidal, antibacterial, and antiviral activities. In this study, we analyzed the components of the venom of the North African scorpion Compsobuthus werneri, which has not been studied before, using LC/MS and isolated an insecticidal peptide (Cw-1). The primary structure of Cw-1 was identified using Edman degradation and de novo sequencing analysis, which showed similarity to chlorotoxin-like peptides.