目次
オーラルセッション
- 第2日 6月23日(木) 10:00~10:20 B会場(409,410)
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2B-O1-1000 PDF
質量分析を活用した新規ミクログリア活性化マーカーの開発研究
Microglial activation is known to cause diseases such as chronic pain. Currently, there is no biomarker of microglial activation that can be easily evaluated. We focused on 24S-hydroxycholesterol (24OHC) in blood as a novel biomarker of microglial activation. An analytical method of 24OHC by LC/MS/MS was developed and validated to investigate its potential as a biomarker of microglial activation in animal model or human.