日本質量分析学会 第70回質量分析総合討論会会

演題概要

ポスター発表

第1日 6月22日(水)  P会場(501,502,503)

タッピングモード走査型プローブエレクトロスプレーイオン化法による質量分析イメージングの溶媒選択性

(1阪大理2阪大院理3JST・さきがけ4阪大院工)
大手虹歩1o大塚洋一2,3孫夢沢2新間秀一4豊田岐聡2

Tapping-mode scanning probe electrospray ionization (t-SPESI) is a extraction-ionization technique using picoliter solvents, which can be applied to mass spectrometry imaging (MSI). Positive ion mode MSI of mouse brain tissue sections was studied using DMF/MeOH binary mixtures and their respective pure solvents. The mixed solvent was found to have the highest number of ion peaks detected, and the physicochemical properties of the solvent were found to influence the extraction and ionization in t-SPESI.