演題概要

オーラルセッション

第1日　6月22日（水）　17:00～17:15　D会場（413，414）

1D-O1-1700（1P-44）　　PDF

ナノ微粒子支援型質量分析による毛髪成分局在解析

(¹福島大・農・ ²ワイエイシイ)
^o草野勇樹¹・ 鹿野仁美¹・ 高橋信行²・ 平修¹

Using a vertical hair-slice section, we compared the components of normal and damaged hair regions using two ionization methods, matrix-assisted laser desorption/ionization and nanoparticle-assisted laser desorption/ionization (nano-PALDI) mass spectrometry. Nano-PALDI is useful for small-molecule and high spatial resolution (5 μm) analyses due to the lack of noise. Thus, clear images were obtained from thin hair samples. In nano-PALDI mass spectrometry imaging, cystine and 18-methyleicosanoic acid as endogenous hair components localized in the cuticle and cortex and cuticle of normal hair, respectively. In contrast, both components were absent in damaged hair.