-- Table of contents --
Reception, Banquet etc. Plenary/Special Lectures
Award Lectures AOMSC Symposium
Evening session & AOMS assembly Symposium
Workshop Poster presentations
Time table

Reception, Banquet etc.

Plenary/Special Lectures

Award Lectures

AOMSC Symposium     < Program >
SessionFundamentals (AOMSC)
OrganizerSeung Koo Shin (POSTECH, Korea)
Scope Fundamental studies of chemical and biological reactions in the gas phase provide a better understanding of elementary reactions in the presence or absence of solvent, counter ions, and other surrounding cage effects. This session will host the fundamental studies of ion-molecule reactions and association; ion dissociation induced by collisional activation, photoexcitation, and charge recombination; and their mechanistic studies by experiments and theory.
SessionProteomics Based on Mass Spectrometry (AOMSC)
OrganizerJong Shin Yoo (Korea Basic Science Institute) & Shu-Hui Chen (National Cheng-Kung Univ. Taiwan)
Scope Mass spectrometry-based proteomics covers a broad range of topics related to protein identification and quantification as well as their widespread use in biomarker discovery and systems biology. This session will host both qualitative and quantitative proteomics, functional proteomics and biomarker discovery, clinical proteomics, phospho-proteomics, glyco-proteomics, other post-translational modification proteomics, and MS informatics for proteomics.
SessionAmbient Ionization Mass Spectrometry (AOMSC)
OrganizerJentaie Shiea (National Sun Yat-Sen Univ. Taiwan) & Kenzo Hiraoka (Yamanashi Univ. Japan)
Scope The ionization of analyte in different states under ambient conditions, known as ambient ionization mass spectrometry, is currently a fruitful research area. The technique is also known for requiring minimal or no sample pretreatment. Much attention has been attracted for applying the techniques in the fields of biomedicine, food safety, antiterrorism, pharmaceuticals, forensic science, and environmental pollution. In this session, the ambient ionization sources including electrospray laser desorption ionization (ELDI), low temperature plasma (LTP) desorption ionization, extractive electrospray ionization (EESI), and direct analysis in real time (DART) will be presented, by scientists responsible for their development or applications.
SessionNanomaterials for Mass Spectrometry (AOMSC)
OrganizerYu-Chie Chen (National Chiao Tung Univ. Taiwan) & Ryuichi Arakawa (Kansai Univ. Japan)
Scope This section is aimed to focus on the applications of nanomaterials in mass spectrometry. Emerging techniques by combining nanoscience and mass spectrometry have led a great advance for the development in both fields. Nanomaterials have attracted great interest to the development of new mass spectrometric methods owing to the large variety of their chemical, physical, and mechanical properties they present. Additionally, affinity based mass spectrometry by using nanomaterials with high surface area as affinity probes for target species is the other rapidly growing area of research. This section will cover the frontiers of research on the nanomaterial-based mass spectrometry.
SessionMetabolomics (AOMSC)
OrganizerRyo Taguchi (Univ Tokyo) & Zeper Abliz (Chinese Acad Med Sci)
Scope Metabolomics is one of the major growing fields in the application of global analysis by mass spectrometry. In metabolomics both identification and quantification of metabolite are important. Thus the construction of databases for real and theoretical metabolites for effective search engine is very important. Multivariate analyses after annotation of metabolites are revealed to be more powerful than that without annotation. In this session, database as an identification tool and their application in life science are discussed.
SessionIsotope & ICP MS (AOMSC)
OrganizerSuresh Aggarwal (HBNI, India)
Scope The isotopic analysis and elemental determination session will focus on the recent advances in thermal ionization mass spectrometry (TIMS) and inductively coupled plasma source mass spectrometry (ICPMS); both quadrupole based and multicollector high resolution systems. The presentations will highlight the applications of TIMS in nuclear, geological and biomedical sciences as well as the advances in the use of collision-reaction cell technology in ICPMS. Specific examples will show the use of negative-TIMS for high accuracy measurements of 11B/10B isotope ratios; possibility of determining 41Ca by using dynamic reaction cell (DRC) in ICPMS for biomedical applications; time dependent concentration profiles of quantum dots present in liver extra cellular fluid after I.V. administration; use of rare-earth elements to trace the pathway of oil fluids to improve the productivity of the crude oil; "in-cell separation" of interferences based on DRC for nuclear technology; and accurate determination of hydrogen isotopes in fuel reprocessing system of fusion reactor.

Evening session & AOMS assembly

Symposium     < Program >
Session Drug metabolism and pharmacokinetics
- metabolite profiling by using mass spectrometry -
Organizer Organized by Makoto Takei (Daiichi Sankyo Co., Ltd.) & Kazuyoshi Nozaki (Astellas Pharma Inc.)
Scope Two years have passed since the FDA guidance on the safety testing of drug metabolites, in other words MIST (Metabolites In Safety Testing) guidance, was published in February 2008. The discovery of disproportionate drug metabolites including unique human metabolites late in drug development can be a serious damage for the drug safety assessment from a ADME standpoint. Therefore characterizing metabolic pathways based on pre-clinical in vitro data and/or animal studies help avoid unnecessary delays in the clinical program. In recent years, the mass spectrometry has been recognized as the most important method for the qualitative and quantitative evaluation of the metabolite profiling. However, it is an undoubted fact that the mass spectrometry is not a perfect methodology for identification and measurement of metabolites in safety testing especially when the authentic standards of the metabolites and stable isotope-labeled compounds for the internal standard are not obtained. In this workshop, the advantages and disadvantages of the mass spectrometric technique related to MIST will be discussed.
Session Mass Spectrometry of Biomolecules - Amino acids, Nucleic acids, Carbohydrates, Proteins, Lipids, etc. - Toward a Global Understanding of Living Systems
Organizer Organized by Akira Motoyama (Shiseido Co., Ltd.) & Naoyuki Yamada (Ajinomoto.Co., Inc.)
Scope As an indispensable tool for the analysis of biomolecules, Mass Spectrometry has been significantly contributing to life science research that tries to understand or control living systems. However, as evidenced by the progress of "OMICS" research, our current knowledge is far from comprehensive understanding of living systems, which is likely because most of collected information is a mosaic of snapshots taken from different angles. The excessive segmentation of research areas, which is ironically a consequence of the recent rapid progress, appears to become an obstacle to stay focused on our principal goals – the global understanding of living systems. Under these circumstances, the session "Mass Spectrometry of Biomolecules" is planned to be an incubator to integrate knowledge and techniques, and to envision innovations, simply by providing a space where frank and active discussions take place between a broad range of acknowledged speakers and audiences. A few slots will be open for presenting your research, so please join us and be part of it!
Session Accuracy and reliability for quantitative analysis
Organizer Organized by Tomoya KINUMI (AIST) & Yasuo MIZOOKU (Sumika Chemical Analysis Service, Ltd.)
Scope "Quantitative analysis" can be defined as the following processes, measurement based on a reliable operation procedure, standard material for the measurement, and validation process of the result. To establish reliable quantification, both suitable standard and method of measurement are needed. Therefore, an improvement of the only technical aspect is insufficient to ensure the quality of measurement. The aim of this session will be focused on the standardization, regulation and traceability of quantitative analysis.
Session Challenge from the fundamental study in mass spectrometry
Organizer Organized by Division of Fundamentals, Ionization and Ion Chemistry in Mass Spectrometry, Toshihide Nishimura (Tokyo Med.Univ.) & Shigeo Hayakawa (Osaka Prefecture Univ.)
Scope Study of the fundamentals including ion-molecule reaction has provided the knowledge regarding mechanisms of ionization and structure analysis. The fundamental knowledge has much contributed to develop the ionization methods such as electrospray ionization (ESI) and matrix-assisted laser dissociation/ionization (MALDI) and dissociation methods such as electron capture dissociation (ECD) and electron transfer dissociation (ETD). New instruments for the fundamental study were also developed. New challenge for mass spectrometry is explored from the fundamental knowledge.
Session Environmental problem and isotope
Organizer Organized by Isotope Ratio Mass Spectrometry, Masao Nomura (Tokyo Institute of Technology) & Takafumi Hirata (Kyoto Univ.)
Scope Global warming is one of the environmental problems of the Earth, and it is cautioned to prevent increase of CO2 emission which is one of the global warming gases. Cavity ring-down spectroscopy (CRDS) has been applied to measure many chemical substances causing air pollution. The narrow spectral properties of semiconductor lasers can resolve rotational energy levels associated with different isotopes. The CRDS has been rapidly developed as a simple method to measure stable isotopic ratios in various chemical species such as CO2 and H2O. Principles and applications of the CRDS will be presented. Analytical methods of isotopic ratios, isotope separation and relationship between isotopes and environmental problems will be discussed.

Workshop     < Program >
Session Instrumentation for Mass Spectrometry is a Branch of Science
Organizer Organized by Takaya Satoh (JEOL Ltd.) & Yasuhide Naito (GPI)
Scope In this workshop session, original developments of or new concepts for mass spectrometers and their components may be discussed. Although implemented technologies of recent commercial available mass spectrometers have been extremely sophisticated and seem to be almost matured, research interests related to the instrumentation will never end. A specialized instrument in fundamental studies, for instance, must be developed at first if one intends to measure m/z and other physical quantities such as ion mobility in parallel; meanwhile in the industry side, there are subjects of making mass spectrometers be portable, miniaturized, optimized for special purposes, or automated. Besides, instrumental developments are essential for ion generation/detection or imaging mass spectrometry. This workshop aims to focus on the attraction and scientific aspects of instrumentation for mass spectrometry through a wide variety of cases.
Session MS for protein science: Advanced technologies make progress with identification, quantitation and structural characterization of proteins.
Organizer Organized by Takao Kawakami (Tokyo Med. Univ.) & Satoko Akashi (Yokohama City Univ.)
Scope Mass spectrometry is now an essential tool in the field of protein science. It has been applied to a variety of researches, including amino acid sequencing, protein identification, quantitation of post translational modifications, analysis of protein conformational changes and observation of large protein complexes. Combined with several separation techniques, fully automated mass measurement facilitated large-scale analysis of complex biological systems. The resulting huge data motivated researchers to form biological knowledge beyond any information focusing on individual molecules, leading to the outcome related directly to our health and diseases. In these contexts, this workshop will cover wide-ranging issues on protein science. Speakers are expected to present the up-to-date progresses in which mass spectrometry is used as a key technology. These presentations would agitate discussion from various viewpoints.
Session Simple introduction of ionization
Organizer Organized by Kunio Awazu (Osaka Univ.) & Shinji Nonose (Yokohama City Univ.)
Scope This session will focus and discuss on the basic and practical issues in mass spectrometric ionization processes. Ionization efficiency of gas-phase analyte and process of analyte formation from condensed phase are suitable for discussion as a practical issue.
Session Unicellular micro-regional analysis and imaging with mass spectrometry
Organizer Organized by Jiro Matsuo (Kyoto Univ.) & Naohiro Tsuyama (Hiroshima Univ.)
Scope Microscopic higher-order structures of biological tissues and cells consist of multiple molecules. New mass spectrometric methods based on MALDI-MS, SIMS and nanoESI have been developed to visualize molecular composition, such as small metabolites, lipids or proteins in tissues and cells. This session will focus on the unique characteristics and technological issues of the microscopic mass spectrometric methods. Various practical applications, which could not be realized with conventional methods, will be presented with current trends and future prospects.
Session Future of Food and food security -- Efficient use and circulation of global environmental resources
Organizer Organized by Division of Tropo Mass Spectrometry, Yasuo Shida (Tokyo Univ. of Pharm. & Life Sci.) & Sadamu Kurono (Osaka Univ., Wako Pure Chemical Industries)
Scope Recently, because we pursued more fruitful and convenient life, food might be polluted by invisible chemicals. In modern agriculture, cultivation field became small area to have most effective yield by applying chemical fertilizer and insecticide. Now pesticide residue became most concern. These problems would destroy nature directly or indirectly and give fatal influence to our future life.
Highly sensitive instrument, mass spectrometry perform serial analysis of separation analysis by connected GC and LC. Now mass spectrometry analysis was recognized not only as pharmaceutical research equipment but also pesticide residual monitoring tool. In this symposium we would like to discuss Food Safety by Mass Spectrometry from various cases.

Poster presentations
Day 1 Wednesday, June 16
Day 2 Thursday, June 17
Day 3 Friday, June 18

Time table
Time table    PDF file [ 93KB ]

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