The Mass Spectrometry society of Japan - The 71st Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lecture

Symposium Sessions (Day1, Day2, Day3)

Basic Sessions (Day1, Day2, Day3)

Young Researchers' Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Special Evening Sessions

Corporate Program

Poster Presentations

Day 3, May 17（Wed.）　　Room P (Foyer, Room 1004-1007)

3P-40　　PDF

Development of Vacuum Differential Mobility Spectrometry Coupled to Liquid Chromatography/ Mass Spectrometry

(1Shimadzu, 2Shimadzu Res. Lab. (Europe), 3Univ. Geneva)
oYoungsoon Hong1, Toshimasa Ishii1, Atsushi Yajima1, Hiroki Maeda1, Kiyoshi Ogawa1, Osamu Furuhashi1, Patrick Knight2, Andrew Entwistle2, Maria Fernanda Cifuentes Girard3, Gerard Hopfgartner3

Differential mobility spectrometry (DMS) separates ions based on the nonlinear change in their mobility between high to low electric fields, which are elicited in a field asymmetric waveform applied to electrodes. This nonlinear change in mobility has less dependence on a molecular weight, and thus DMS can be useful for separation of structural isomers and isobars. The mobility coefficient in DMS can be expanded by nonlinear terms of E/N (E: Electric field strength, N: Gas density). Therefore, higher E/N gives greater change in mobility and result in higher resolution. We have developed vacuum DMS, which reduces gas density N and gives higher E/N than conventional atmospheric DMS. Here we introduce the principle of vacuum DMS and show the examples of analyses using LC-vacuum DMS-MS.