The Mass Spectrometry society of Japan - The 71st Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lecture

Symposium Sessions (Day1, Day2, Day3)

Basic Sessions (Day1, Day2, Day3)

Young Researchers' Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Special Evening Sessions

Corporate Program

Poster Presentations

Day 3, May 17（Wed.）　　Room P (Foyer, Room 1004-1007)

3P-26　　PDF

Basic investigation of laser desorption ionization with new nanopillar structured substrates

(1Osaka Univ., 2Hokkaido Univ., 3Hokkaido Univ., 4Osaka Univ.)
oJunichi Osuga1, Ryota Saito2, Yasutaka Matsuo3, Hiroshi Furutani4, Michisato Toyoda1

We developed and evaluated new nanopillar structure substrate for laser ionization. We examined several types of nanopillar substrates, commercially available Surface Enhanced Raman Spectroscopy (SERS) substrate and stainless-steel plate for MALDI. As a result, ionization efficiency is depending on its nanopillar structure drastically. Simple Si nanopillar and thin Au layer on Si nanopillar structure were not observed Gly related ions, however Au-AlO3-Au (metal-insulator-metal; MIM) structure substrate shows higher ion intensity than SERS substrate. In this experiment, MALDI plate shows several times higher ion intensity than that of MIM substrate. In conclusion, we found not only nanopillar structure was effective for ionization but also how to make metal layer was a key for better ionization.