The Mass Spectrometry society of Japan - The 71st Annual Conference on Mass Spectrometry, Japan

Abstract

Poster Presentations

Day 3, May 17(Wed.)  Room P (Foyer, Room 1004-1007)

Analysis of Isomeric Peptides by MS/MS with Hydrogen Attachment Dissociation

(1AIST, 2Shimadzu)
oDaiki Asakawa1, Shinichi Iwamoto2, Koichi Tanaka2

In this study, we focused on the reaction of the peptide ions containing isoaspartic acid residue (isoAsp) and hydrogen atoms in an ion trap mass spectrometer. [zn + C2H5ON]+ was observed as a specific signal for the isoAsp. The hydrogen attachment dissociation is useful for the quantitative analysis of peptide containing isoAsp.