The Mass Spectrometry society of Japan - The 71st Annual Conference on Mass Spectrometry, Japan

Abstract

Symposium Sessions

Day 3, May 17(Wed.) 15:21-15:43 Room A (Special Conference Room)

GeLC-FAIMS MS Workflow for In-Depth Top-Down Proteoform Analysis

(1Ehime Univ., 2CAU)
Ayako Takemori1, Philipp Kaulich2, Andreas Tholey2, oNobuaki Takemori1

In top-down proteomics, sample pre-fractionation prior to mass spectrometry analysis allows for an increase in the number of detectable proteoforms. We present a GeLC-FAIMS MS workflow for multidimensional proteoform separation and its application for deep top-down proteomics.