The Mass Spectrometry society of Japan - The 71st Annual Conference on Mass Spectrometry, Japan

Abstract

Poster Presentations

Day 2, May 16(Tue.)  Room P (Foyer, Room 1004-1007)

Analyses of biopharmaceuticals using high-resolution multi-turn TOF-MS

(1Shimadzu, 2Osaka Univ.)
oHiroyuki Miura1, Yusuke Tateishi1, Hiroko Morinaga1, Koichi Kimura1, Tetsuo Iida1, Junna Nakazono1, Masaru Nishiguchi1, Osamu Furuhashi1, Daisuke Okumura1, Yuki Yamaguchi2, Susumu Uchiyama2

In recent years, the development of new biopharmaceuticals such as next-generation antibodies and viral vectors has been promoted. In the field of quality control of biopharmaceuticals, accurate analyses of their chemical modification, decomposition, and aggregation have an important role. For this purpose, we have been developing a high-resolution multi-turn TOF-MS. In this presentation, we demonstrate the results of monoclonal antibody analyses and other applications.