The Mass Spectrometry society of Japan - The 71st Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lecture

Symposium Sessions (Day1, Day2, Day3)

Basic Sessions (Day1, Day2, Day3)

Young Researchers' Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Special Evening Sessions

Corporate Program

Poster Presentations

Day 1, May 15（Mon.）　　Room P (Foyer, Room 1004-1007)

1P-40　　PDF

Analysis of Metabolites in Hair by Liquid Chromatography-Mass Spectrometry with Ion Mobility and Laser Desorption/Ionization Mass Spectrometry

(1Toyama Pref. Univ., 2Toyama Pref. Univ., 3Kanazawa Univ.)
oRiko Takata1, Mai Yamakawa2, Taichi Shimazaki2, Shigehiro Karashima3, Issey Osaka1,2

Human blood metabolites are accumulated into hair. The metabolites in the hair reflects the time-averaged composition in the blood circulation. Therefore, the analysis of the metabolites in the hair allows to assess human health. It has become increasingly important to establish a rapid and comprehensive analytical method of its metabolites for the assessment. In this study, we developed the LC/MS coupled with ion mobility for the analytical method for targeted quantitative and non-targeted qualitative analysis simultaneously. In addition, laser desorption/ionization mass spectrometry imaging was also applied for the metabolite profiling.