The Mass Spectrometry society of Japan - The 71st Annual Conference on Mass Spectrometry, Japan

Abstract

Poster Presentations

Day 1, May 15(Mon.)  Room P (Foyer, Room 1004-1007)

Profiling of anti-diabetic components of green tea in different cultivars and crop seasons

(Kyushu Univ.)
oYoshinori Fujimura, Tomomi Ichinose, Mototsugu Watanabe, Mao Yamamoto, Motofumi Kumazoe, Hirofumi Tachibana

The inhibition of dipeptidyl peptidase (DPP)-IV enzyme is essential for the control of hyperglycemia in diabetes mellitus. It has been reported that green tea (Camellia sinensis L.) possesses DPP-IV inhibitory activity, but no comparison among green tea cultivars or identification of active components has been reported. We have reported that metabolic profiling (MP) technique, which visualizes the potential relationship between the amount of samples and their bioactivity, is effective in assessing the functionality of foods/agricultural products and identifying the components involved in the functionality. However, there are no reports on MP-driven bioactivity evaluation of green tea cultivars related to DPP-IV inhibitory activity. In this study, we examined the DPP-IV inhibitory activity of green tea in different cultivars and crop seasons and found components related to bioactivity using the MP method.