演題概要

ポスター発表

第3日　5月13日（水）　　P会場（1008/09）

3P-09　　PDF

生体分子のLC/MS分析向け新規高質量分解能質量分析計の開発

(¹島津・ ²島E・ ³SRL)
^o三浦宏之¹・ 立石勇介¹・ 出水秀明¹・ 古橋治¹・ 谷口純一¹・ 小河潔¹・ 丸野浩昌¹・ 中冨学郎²・ 藤田遼³・ Shchepunov, Vyacheslav³・ Rignall, Michael³・ Harley, Stuart³・ 和気弘明³・ Chadbourne, Jeff³

We have developed a novel multi-turn TOF-MS (MTOF). This system avoided the "overtaking " that has been encountered in conventional MTOF, and achieved high resolving power while keeping its size compact. We constructed LC-MTOF-MS and evaluated the performance. Mass resolving power higher than 150k (FWHM) and instrument detection limit of approximately 3 amol were achieved. Furthermore, MS analyses of biological molecules were performed. Isotopic peaks of cytochrome c (approximately 12kDa, 8+) were clearly separated.