日本質量分析学会 第68回質量分析総合討論会会

演題概要

ポスター発表

第2日 5月12日(火)  P会場(1008/09)

質量分析を用いた大腸がん細胞株の¹³C代謝フラックス解析

(阪大院情報)
o近藤佑哉島知輝岡橋伸幸松田史生

¹³C-metabolic flux analysis (¹³C-MFA) using mass spectrometry is one of the methods for measuring metabolic flux. We applied this method for colorectal cancer cells including HCT116, WiDr and DLD-1 to extract features of central carbon metabolism of colorectal cancer cells. The Warburg effect was confirmed in all three cell lines. On the other hand, there was a difference in glutaminolysis, although glutamine uptake was approximately the same.