日本質量分析学会 第68回質量分析総合討論会会

演題概要

ポスター発表

第2日 5月12日(火)  P会場(1008/09)

周波数分割多重化 HPLC-MS の多重度増大に関する研究:6HPLC-1MS の開発

(名工大院工)
o先田廉岸博香北川慎也大谷肇

A demand to enhance the throughput in HPLC-MS is required for analyzing a large number of samples. One of the instance for high throughput HPLC-MS is a multiplex HPLC-MS, in which a single MS and multiple HPLCs are connected. Recently, we proposed novel multiplex HPLC-MS based on frequency division multiplexing (FDM), and hyphenation of two HPLCs and one MS (2HPLC-1MS) was successfully demonstrated. In this presentation, we investigated about the increase in multiplicity to enhancing the analytical throughput. The parameters to enhancing the multiplicity is numerically studied. Moreover, new interfaces including ion gates for the signal modulation for 4HPLC-1MS and 6HPLC-1MS were developed, and the signal separations in the power spectrum, obtained by Fourier transform, were successfully achieved.