日本質量分析学会 第67回質量分析総合討論会

演題概要

ポスター発表

第3日 5月17日(金)  P会場(多目的ホール)

血中チオ硫酸塩測定における前処理法の改良

(北大院医)
o邵旻蓉的場光太郎兵頭秀樹的場智子齋藤厚子神繁樹

In the measurement of blood thiosulfate with LC-MS/MS, standard samples for the calibration curve must use a control blood as solvent because blood has matrix effects on the measurement of thiosulfate concentration. Therefore, a lot of control blood is required to create a calibration curve. In this study, the sample preparation was improved using an ultrafiltration, and it was possible to create the calibration curve with distilled water as solvent instead of blood. Though our ultrafiltration method is a simple process for sample preparation, it is very useful for measuring the thiosulfate concentration in blood samples.