Program

Poster Presentations

Day 4, May 18（Fri.）　　Poster

4P-33　　PDF

Adding Mass Detection to LC/UV-Based Workflows for Routine Analysis and Monitoring of Biologics in Development and Quality Control Laboratories

(¹Nihon Waters, ²Waters)
^oMasayo Yabu¹, Kenji Hirose¹, Maki Terasaki¹, Brooke Koshel², Ximo Zhang², Robert Birdsall², Yinq Yu²

In this study, we present a strategy for the acquisition of optical data with added mass detection for enabling identification of a model peptide, eledoisin, and its impurities using compliant-ready software. With processing and reporting methods in place, user error is eliminated, and treatment of the data is automated. Furthermore, any standards or samples not meeting established criteria are flagged for user intervention, with added mass detection readily allowing for further interrogation of samples that do not meet specification.