The 10th Asia-Oceania Mass Spectrometry Conference (AOMSC2025) - organized by the Mass Spectrometry Society of Japan

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Poster Presentations

Day 4, June 25(Wed.) 

Room P (Maesato East, Foyer, Ocean Wing)

Analysis of Daily Urine Samples of Pregnant Rats Unveils Developmental Processes of Fetus as Well as Physiological Changes of Mother Rats

(Beijing Normal Univ)
oYouhe Gao

During pregnancy, both the fetus and mother experience significant physiological changes. Urine proteins can mirror these changes. This study used magnetic nanobeads to enrich low - abundance proteins and analyze daily urine protein changes in pregnant rats. Over 3,455 urine proteins were identified. Compared to the control group, the pregnancy group showed fetal and maternal dynamic changes. In early pregnancy, there was blastocyst formation; in mid - stages, embryonic development and organ morphogenesis; and in late pregnancy, maternal lactation - related changes. The results suggest urine protein analysis can reflect pregnancy - related physiological alterations, highlighting its potential for pregnancy health monitoring. Focusing on daily urine protein variations may uncover more detailed physiological process information.