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Poster Presentations
Day 3, June 24(Tue.)
Room P (Maesato East, Foyer, Ocean Wing)
- 3P-PM-03
Development of a GC-MS Method for Detecting 23 Commonly Abused Drugs in Taiwan
(TVGH)
oHsiaochia Liao, Yanchiao Mao
Drug abuse or Substance abuse, as defined by the World Health Organization (WHO), refers to the harmful or hazardous use of psychoactive substances, which may lead to dependence syndrome. Despite strict regulations in various countries, drug abuse cases continue to rise. According to statistics from Taiwan Food and Drug Administration (TFDA), the prevalence of drug abuse has been increasing annually. Heroin, Methamphetamine, and Ketamine are the top three abused substances reported by medical institutions, highlighting the severe impact of drug abuse on human health.
This study aims to develop an analytical method for detecting 23 commonly abused drugs in Taiwan using gas chromatography-mass spectrometry (GC-MS) with full-wavelength scanning mode (Full-Scan), coupled with an SH-I-5Sil MS column. The total analysis time for each sample is 15.13 minutes. The method achieves a Limit of Detection (LOD) of 5 μg/mL and a linear range of 5–60 μg/mL. The accuracy, precision, and recovery rate of the method demonstrate reliable performance.
The developed method provides an effective and validated approach for forensic toxicology and drug analysis, offering a valuable reference for identifying illicit substances. The high sensitivity and efficiency of this method enable rapid and accurate detection, contributing to the ongoing efforts in drug abuse prevention and law enforcement.