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Poster Presentations
Day 3, June 24(Tue.)
Room P (Maesato East, Foyer, Ocean Wing)
- 3P-AM-27
Imaging Analysis of Steroids in Adrenal Glands Using SALDI/MS with Metal Films
(1Toyama Prefectural University, 2Kanazawa University)
oKokoro Okawa1, Riko Takata1, Shigehiro Karashima2, Issey Osaka1
Analyzing steroids in biological tissues is important for revealing their physiological roles. This study compared matrix-assisted laser desorption/ionization mass spectrometry (MALDI/MS), surface-assisted laser desorption/ionization mass spectrometry (SALDI/MS) with metal films, and matrix-enhanced SALDI/MS for the detection of steroids in adrenal glands. MALDI/MS detected ions of derivatized steroids, while SALDI/MS achieved strong signals without derivatization. It was shown that the steroids that could be detected with high sensitivity vary depending on the ionization method.