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Plenary Lectures Day1　Day2　Day3　Day4

MSSJ Award Lectures Day1

Oral Sessions Day2　Day3　Day4

Poster Presentations Day1　Day2　Day3　Day4

Late-Breaking Posters Day1

Luncheon Seminars Day2　Day3　Day4

Teatime Sessions Day3

Corporate Posters Day2　Day3　Day4

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Day 2, June 23（Mon.）　

Room P (Maesato East, Foyer, Ocean Wing)

• 2P-CP-03

REVOLUTIONIZING TRANSLATIONAL RESEARCH: LARGE-SCALE TARGETED PRM PROTEOMICS ASSAYS ENABLED BY STELLAR MASS SPECTROMETER (MS)

(¹Thermo Fisher Scientific, ²Thermo Fisher Scientific San Jose, ³Thermo Fisher Scientific Singapore)
Scott Peterman¹, Qingling Li², ^oNicole Zhang³

Targeted mass spectrometry assay development for biomarker validation is no simple task. Although, the alure of finding a conclusive biomarker to indicate the presence of disease seems simple and straightforward in the discovery phase, the verification step is a painstakingly costly process. While traditional methods of analyzing target proteins defer to immunological or affinity-based assays, they suffer from lack of specificity and sensitivity. This is of critical concern for potential low abundant biomarkers in highly complex biomatrices. Biomarker verification by Thermo Scientific^TM Stellar^TM MS provides increased sensitivity, greater specificity and extended accuracy. Here, we showed a streamlined workflow from generating a Skyline file to select LC peaks, creating PRM methods, and exporting MS results for further analysis within 3-4 days.

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