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Day 2, June 23（Mon.）
Room P (Maesato East, Foyer, Ocean Wing)
- 2P-CP-02
LC-MS WORKFLOWS FOR DIVERSE OMICS ANALYSIS OF PLASMA SAMPLES IN A MINI CANCER COHORT USING THE ORBITRAP ASTRAL MASS SPECTROMETER
(1Thermo Fisher Scientific San Jose, 2Thermo Fisher Scientific Singapore)
Kevin Yang1, oNicole Zhang2
The prognosis for cancer patients improves significantly with earlier diagnoses. Current diagnostic methods, such as biopsies and imaging scans, are either invasive or not always easily accessible. In contrast, blood plasma analysis has gained acceptance as a promising approach for biomarker detection. Recent studies have shown that mass spectrometry based multi-omics analysis enhances accuracy and precision in disease diagnosis due to improved diagnostic features. In our study, we demonstrate that the Orbitrap Astral mass spectrometer, coupled with the Vanquish Neo UHPLC system, can serve as a single LC-MS platform to perform comprehensive analyses of proteomics, metabolomics, and lipidomics. This effort lays the foundation for diverse omics analysis in translational research.