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Oral Sessions
Day 2, June 23（Mon.） 14:40-14:55
Room B (Maesato Center)
- 2B-O2-1440
Synthetic Antioxidants as New Pollutants Revealed by Mass Spectrometry: From Environmental Occurrence to Human Exposure
(Shandong Univ.)
oRunzeng Liu, Xiaoxia Feng, Xiaomeng Ji
Synthetic antioxidants, including synthetic phenolic antioxidants (SPAs) and organophosphite antioxidants (OPAs), are widely used to retard oxidative reactions and lengthen shelf life of products. Limited information can be found on environmental pollution caused by these chemicals. We developed high sensitivity mass spectrometry methods to analyze these new pollutants. SPAs were widely identified in sludge and indoor dust, with 2,6-di-tert-butyl-4-methylphenol (BHT) was the primary congener. Human internal exposure to SPAs was confirmed by their detection in human serum. In agreement with environmental samples, BHT was the primary congener in human serum. In contrast to human serum, BHT was observed at very low concentrations in human urine, while 3,5-di-tert-butyl-4-hydroxybenzoic acid (BHT-COOH) was detected at high concentrations, suggesting the biotransformation from BHT to BHT-COOH in human before urinary excretion. As for OPAs, they can not be detected in most environmental samples. However, the oxidation products of OPAs can be detected at high concentrations in indoor dust. Besides, abundance of oxidation products of OPAs, such as tris(2,4-di-tert-butylphenyl) phosphate, increased significantly in Artic air since 1994. Mass spectrometry analysis provides new knowledge on environmental occurrence and human exposure of synthetic antioxidants.