演題概要

1P-27

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電荷検出質量分析：メガダルトン超の巨大分子の質量測定のための新しい分析法

(¹日本ウォーターズ・ ²ウォーターズ)
^o廣瀬賢治¹・ 矢田絵都子¹・ 寺崎真樹¹・ Haris, Anisha²・ Giles, Kevin²・ Yu, Ying Qing²・ Preece, Steve²

In recent years, pharmaceutical modalities have shifted to macromolecules with masses exceeding 1 million Da (megadalton), such as gene therapy and cell therapy. The mass range that can be measured with existing commercial mass spectrometers, such as time-of-flight mass spectrometers, is generally up to megadalton, and the emergence of a new technology that can handle the mass analysis of the above new modalities has been desired. Here, we introduce an application example using Charge Detection Mass Spectrometry (CDMS), a new analytical technique for the measurement of macromolecules.