演題概要

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第2日 5月19日(木) 9:20~9:40 C会場(星雲2)

Aspergillus nidulansの二次代謝物のGC/MSおよびLC/MS/MS分析とセスキテルペン生成関連遺伝子の探索 V. LO8910およびLO8925株

(1奈良女大院人間文化2奈良女大理3奈良女大古代4名大院医)
o塚本奈緒1木村知子2鈴木孝仁3紅朋浩4竹内孝江2

The effects of modified expression of several sesquiterpene biosynthesis genes in the genome of A. nidulans were investigated by HRMS, NMR and Circular Dichroism Spectroscopy. In expression-enforced strains, LO6191 for AN3277 gene and LO8910 and LO8925 for AN3280 gene of A. nidulans, three peaks were detected in the extracted ion chromatogram (EIC) at m/z 204, which corresponds to the molecular ions of sesquiterpenes including (+)-aristolochene.