演題概要

ポスター発表

第1日 5月18日(水)  ポスター会場(うめ)

リボソームタンパク質をバイオマーカーとしたMALDI-TOFMSによるAspergillus fumigatus類縁真菌の迅速識別

(1産総研環境管理2千葉大真菌医セ)
o佐藤浩昭1中村清香1田中玲子2高橋弘喜2矢口貴志2

In this study, MALDI-TOFMS of ribosomal proteins was applied to discriminate five species (28 strains) belonging to pathogenic fungus, the Aspergillus section Fumigati. The masses of the 29 types of ribosomal proteins used as biomarkers were identified by MALDI-TOFMS. A phylogenetic tree were constructed based on the profiles of ribosomal protein biomarkers. The sample strains were divided into clusters reflecting the species. These results demonstrated ribosomal protein profiling method using MALDI-MS would be a sufficiently high-throughput technique for rapid discrimination of closely related Aspergillus species.