日本質量分析学会　第67回質量分析総合討論会
Japanese

Abstract

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Timetable

Plenary Lectures

Society Featured Lecture

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Oral Sessions (Day1, Day2, Day3)

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Oral Sessions

Day 3, May 17（Fri.）　15:25-15:45　Room D (202)

3D-O2-1525　　PDF

Cellular Scale Imaging Mass Spectrometry by Combining DIUTHAME and Stigmatic-Type Mass Microscope

(1GPI, 2Hamamatsu Photonics)
oTsuyoshi Hirao1,2, Yasuhide Naito1

Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) is increasingly used for a variety of applications. One drawback to MALDI-IMS is its spatial resolution, which is restricted by laser scanning and matrix crystalline sizes. Alternatively, stigmatic-type mass microscope detects ion distributions of analytes within a laser spot and can provide a high spatial resolution irrespective of the focused laser beam diameter. Recently, desorption ionization using through hole alumina membrane (DIUTHAME) as a matrix-free laser desorption/ionization method has been developed by the authors’ group. The proposed combination was examined along with a newly-invented detector for stigmatic-type mass microscope.