オーラルセッション
- 第3日 5月17日（金） 15:45～16:05 D会場（202）
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3D-O2-1545 PDF
走査型プローブエレクトロスプレーイオン化法のサンプリングイオン化過程
Tapping-mode scanning probe electrospray ionization (t-SPESI) realizes the ambient sampling and ionization (ASI) with a single capillary probe. In order to improve the ASI efficiency in t-SPESI, the understanding and the control of charged solvent is necessary. We developed the measurement system by which the fast acquisition of multiple mass spectra at a certain sample position in order to understand the time course of ion signals during ASI. The ion signal was increased immediately after the stage movement and it was decreased exponentially with increasing time. This result indicates that the molecules on substrate was extracted and consumed for the electrospray. Next, the time course of the probe displacement and the ion signals during a single sampling and ionization event are simultaneously measured for the understanding of the dynamic change of liquid bridge at the probe apex. It was found that the extension time of liquid bridge until its breakage and the ion detection time after the breakage of liquid bridge are correlated with the surface tension and the viscosity of solvent, respectively. Moreover, the effect of experimental parameters of t-SPESI onto the ASI efficiency will be discussed.