Abstract

Poster Presentations

Day 3, June 12（Wed.）　　Room P1 (Multipurpose Hall)・Room P2 (Conference Room 101+102)

Differential mobility spectrometry (DMS) separates ions based on the nonlinear change in their mobilities between high to low electric fields, which are elicited in a field asymmetric waveform applied to electrodes. This nonlinear change in ion mobility has less dependence on a molecular weight, and thus DMS can be useful for separation of structural isomers and isobars. The mobility coefficient in DMS can be expanded by nonlinear terms of E/N (E: Electric field strength, N: Gas density). Therefore, higher E/N gives greater change in mobility and results in higher resolution. We have developed vacuum DMS, which reduces gas density N and gives higher E/N than conventional atmospheric DMS. We showed the examples of analyses using LC-vacuum DMS-MS at this conference last year. Now, we found that separation ability in vacuum DMS can be improved by optimizing conditions of the electric field. Here we show the details of the improvement with analysis examples.

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