The 72nd Annual Conference on Mass Spectrometry, Japan
Date:
Mon, Jun 10, - Wed, Jun 12, 2024
Venue:
Tsukuba International Congress Center (Takezono, Tsukuba City, Ibaraki Prefecture 305-0032, Japan)
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Abstract

Poster Presentations

Day 2, June 11(Tue.)  Room P1 (Multipurpose Hall)・Room P2 (Conference Room 101+102)

2P-15
PDF

Development of Cellulose-Paper with Functional Group for Rapid Analysis of Metabolites in Biofluid

(1OUJRAL, 2Osaka Univ., 3Osaka Univ., 4Osaka Univ. Dent. Hosp.)
oJunichi Osuga1,2, Akihide Sugawara3, Hiroshi Uyama3, Misa Okada4, Takenori Nozaki4, Michisato Toyoda1,2

We developed novel cellulose paper with functional group for medical diagnosis by metabolites analysis. Polydopamine, chitosan and citric acid were examined as a preliminary test by standard and saliva sample. As a result, we succeeded to recover, concentrate, derivatize and analyze by GCMS. Further we could roughly estimate limit of detection (LOD). It was about 0.65 and 0.51 pg for glycine and 2-isopropyl malic acid respectively. It means we obtained almost same as conventional method.