The 72nd Annual Conference on Mass Spectrometry, Japan
Date:
Mon, Jun 10, - Wed, Jun 12, 2024
Venue:
Tsukuba International Congress Center (Takezono, Tsukuba City, Ibaraki Prefecture 305-0032, Japan)
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Abstract

Poster Presentations

Day 2, June 11(Tue.)  Room P1 (Multipurpose Hall)・Room P2 (Conference Room 101+102)

2P-14
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Correlation Between Sample Thickness and Shift of m/z Value in SALDI/MS Imaging

(1Toyama Pref. Univ., 2KYOCERA)
oKotaro Hashimoto1, Taichi Shimazaki1, Kyosuke Kaneda2, Shuhei Yamamoto2, Issey Osaka1

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI/MS) with a time-of-flight mass spectrometer is a useful tool for investigating distribution of biomolecules. However, it is difficult to analyze non-conductive materials due to charge-up effects in the MALDI/MS. We have proposed surface-assisted laser desorption/ionization mass spectrometry imaging (SALDI/MSI) using thin metal films that could add conductivity to the sample surface. In this study, the correlation between the thickness of the sample and the shift of m/z value was evaluated.