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Poster Presentations
Day 1, June 10（Mon.） Room P1 (Multipurpose Hall)・Room P2 (Conference Room 101+102)
- 1P-27
Charge Detection Mass Spectrometry: A Novel Analytical Method for the Mass Measurement of Macromolecules with Super-Megadalton
(1Nihon Waters, 2Waters)
oKenji Hirose1, Etsuko Yada1, Maki Terasaki1, Anisha Haris2, Kevin Giles2, Ying Qing Yu2, Steve Preece2
In recent years, pharmaceutical modalities have shifted to macromolecules with masses exceeding 1 million Da (megadalton), such as gene therapy and cell therapy. The mass range that can be measured with existing commercial mass spectrometers, such as time-of-flight mass spectrometers, is generally up to megadalton, and the emergence of a new technology that can handle the mass analysis of the above new modalities has been desired. Here, we introduce an application example using Charge Detection Mass Spectrometry (CDMS), a new analytical technique for the measurement of macromolecules.